Asthma is a complex disorder characterized by variable and recurring symptoms, airflow obstruction, bronchial hyper-responsiveness, and underlying inflammation. Although asthma is commonly thought of as a disease of children and young adults, a significant percentage of the older adult population is affected and carry a higher rate of morbidity and mortality from the disease. This book examines the causes, complications and treatment of asthma with topics including mathematical modelling in aspirin-induced asthma; the role of neuroimmune and psychological systems in the pathophysiology of bronchial asthma; special considerations of asthma in older adults; changes in the respiratory epithelium in bronchial asthma; and epidemiology of asthma during pregnancy.
As the series title implies each Clinician s Desk Reference will be a practical resource and a daily aid for physicians in the hospital setting and in primary care. Asthma is one of the most important chronic disorders in the developed world. Evidence from around the world shows the prevalence of asthma has increased considerably since 1975, and now affects around 7.2% of the world population (about 100 million individuals). In the UK asthma is now the most common chronic disease affecting all age groups with approximately 11% of the population being diagnosed as having asthma at some time in their lives. Understanding of the basic mechanisms involved in the pathogenesis of asthma has improved dramatically over the past 20 years. Along with this increase in basic scientific knowledge, randomised clinical trials have produced evidence to guide clinicans in how to manage patients with asthma. The book covers edipdemiology, diagnosis and management, and takes a look at future developments. The authors highlight the under diagnosis of occupational asthma and emphasise the importance of effective patient education, particularly asthma action plans. There are ten clinical cases dealing with common diagnostic and management problems, frequently asked questions and appendices containing resources for patients and clinicians including useful websites, information leaflets and major references.
Asthma sufferers number approximately 200 million worldwide, with 15-20 million of those in the United States. Multiple comorbid conditions occur with asthma, including rhinitis, rhinosinusitis, gastroesophageal reflux disease, sleep apnea, vocal cord dysfunction syndrome, obesity, and chronic obstructive pulmonary disease (COPD). Without identifying and caring for comorbid conditions, asthma cannot be treated appropriately. Comorbidity of allergic diseases emphasizes that we must understand more about why different organs in individuals express allergy and others do not. The increase in multiple allergies occurring in a single patient makes the global burden even more complex, and an integrated approach to diagnosis and new treatment strategies and preventative approaches are required. Asthma: Comorbidities, Coexisting Conditions, and Differential Diagnosis is the first volume to provide a centralized, a comprehensive clinical reference on the diagnosis and management of the comorbid conditions that affect asthma. Because comorbid conditions of asthma have not yet been included in international and national management guidelines, this volume will help fill a gap in current clinical knowledge, aiding physicians in delivering optimal patient care. Written and published in conjunction with the World Allergy Organization (WAO), this book consists of the latest research and reviews of current theory and practice, the most effective advances in the diagnosis and management of asthma and its co-morbidities, and insights into the fundamentals of asthma and its co-morbidities. It presents scientifically-based medicine for each comorbid condition as it relates to asthma.
Asthma is a common chronic inflammatory condition of the airways which causes coughing, wheezing, shortness of breath and tightness of the chest. Asthma attacks can be triggered by exposure to allergens, physical exertion, stress, or can be aggravated as a result of common coughs and colds. Over 5 million people in the UK and over 6% of children in the US suffer from Asthma, and a recent increase in prevalence is thought to be attributed to our modern lifestyle, such the changes in housing, diet and a more hygienic environment that have developed over the past few decades. Asthma: The Facts is a practical guide to asthma, suitable for those who suffer from asthma, their families, and the health professionals that treat them. It details how a diagnosis of asthma is reached, and what treatments are available to successfully manage the condition and prevent attacks on a day-to-day basis. The book contains advice on proactive changes which can be made to lifestyles, such as avoiding allergens, as well as how to cope with an attack, and how to administer the relevant treatment effectively. The authors conclude that whilst there is currently no cure for asthma, by taking a proactive, self-directed approach to management, its impact on the patient and their lives can be significantly reduced.
This third edition of Gershwin and Halpern's classic text, Bronchial Asthma, has been completely rewritten and expanded to include, from a variety of disciplines, the latest techniques and developments in the clinical diagnosis and treatment of asthma. With its new patient-oriented chapters on living with asthma, the book will empower the internist, the family practitioner, and the specialist in their struggle to reverse the current trend of increasing asthma mortality and to improve the quality of life of their patients and their families. The editors have selected authoritative contributors to Bronchial Asthma, organizing it into four comprehensive parts: I. Definitions and Host Responses to Bronchospasm defines asthma by analyzing its epidemiology, pathogenesis, and genetic roots, and illuminates the roles of mast cells and eosinophils. Chapters also cover the use of the pulmonary function laboratory and the differential diagnosis of asthma in children and adults. II. Patient Management introduces the latest thinking and techniques about treatment and management of patients, including allergic evaluation, radiological treatment, the role of immunotherapy, the differential management of status asthmaticus, the management of pregnant asthmatics, and an evaluation of unconventional therapies. III. Special Clinical Problems explores respiratory tract infections, the roles of anti-inflammatory agents, food additives, air pollution, aspergillosis, and occupational asthma. Four new chapters analyze exercise-induced asthma, asthma's relationship with chronic sinus disease, and the cross-cultural treatment of asthma in Europe and Japan. IV. Living with Asthma, an entirely new section, examines asthma in school children, athletes and asthma, legal issues for asthmatics, the psychology of asthma, and the use of prospective disease management.
Produktionsjahr: 2014 Medium: Blu-ray Disc Titel: Asthma Uebersetzungstitel: Asthma Zusammengestellt: Pilling, Barney Autor: Hoffman, Jake Komponist: Noseworthy, Mark Regisseur: Baird, Tracey // Haeussner, Noah C. // Hoffman, Jake // Meurer, Stephan
Asthma has rapidly become one of the most common chronic illnesses of the Western world, and its prevalence continues to rise, with the proportion of patients with more severe diseases also increasing. Faced with this problem, more researchers are focusing on the causes, mechanisms, and pathophysiology of asthma. The major hopes are that more effective drugs will become available and that preventive measures can be instituted. Increasingly, molecular and cell bi- ogy approaches are being used to characterize and understand the mechanisms of the inflammatory process that is typical of the asthmatic airway. This volume on Asthma: Mechanisms and Protocols in the Methods in Molecular Medicineseries provides an overview of the molecular mechanisms involved in asthma by p- viding extensive protocols that are being used in asthma research. Briefly, it c- ers details of methods for obtaining cells from the airways, analysis of gene and protein expression in the limited clinical samples from asthmatic airways, use of molecular and cellular tools for studying cytokine expression and release, studies of asthma-related genes and genetic polymorphisms, and understanding the - fects of asthma treatments. With such coverage, the volume ties in several dis- plines, including allergy and immunology, cell biology, pharmacology, and histology. We have continued in the spirit of the series to provide a bench book for day-to-day use.
Discusses the recent findings on the biology and pharmacology of asthma, in 27 papers that constitute the proceedings of a ten-day workshop in Erice, Sicily, May 1991. Among the topics are airway neuropeptides, platelets and asthma, bronchial asthma and pulmonary gas exchange, and the management of